Your Health, Our Mission.

Did you know banking your microbiome could save your life?

What is Autologous FMT – also known as a-FMT?

Autologous Fecal Microbiota Transplantation (a-FMT) is where a person banks or conserves their own microbiome by providing a sample of their stool when they are in a healthy state  1–3. At some later time point, when ready, the same person receives their own microbiome in capsule form,  serving as their own donor for a-FMT.  The idea of a-FMT has been shown to be a well-tolerated option with minimal side effects2,3,5,11. Research has shown that a-FMT can induce rapid restoration of the gut microbiome following gut disruption such as antibiotics and it has been suggested that a-FMT may be a promising strategy to help modulate one’s own gut microbiome 1, 4-6.

At Novel Biome, we collect and store your microbiome (your stool sample) in your current healthy state to be later used in the event of later microbiome damage. Once we receive your sample, we utilize our state-of-the-art lab and best in practice lab manufacturing standards to process your sample into highly concentrated oral capsules. We use only your unique microbiome, allowing you to have your healthy microbiome ready when you need it!

What are the Benefits / Advantages of Conserving or Using Your Own Microbiome?

Your microbiome = your best fit

Best Fit

Important personal attributes such as genetics, diet, and environmental exposures, impact your microbiome 3,7. Research has shown that similarities in microbial composition are important for FMT success 3,8–10

a-FMT reduces the potential for donor-recipient microbial interactions and incompatibilities 3,8,9. By banking or conserving your own microbiome, you are working with your most ideal donor…..YOU!

Increased Safety

Increased Safety

a-FMT has been shown to be safe and is able to proactively reduce antibiotic resistance genes, reduce intestinal inflammation and be effective for gut microbiota restoration 2,3,6,11.

Banking your own microbiome during a healthy state has a more desirable safety profile than traditional FMT 2,3,5,6.  By banking your own microbiome, you are reducing the possible risks associated with donor-recipient mismatch and any transfer of unwanted donor characteristics 2,3,5,6,12–17.

Personalized, a perfect match

Personalized

The overall composition of your microbiome can change from day to day depending on diet and other environmental exposures 6,18. Your microbiome is unique to you, and preserving it at its healthiest is an invaluable asset to you and your future health 1–4.

A-FMT provides you with a fully compatible personalized microbiome, which has been shown to be associated with a markedly improved response to FMT 4.

Why might you consider doing a-FMT?

There are many reasons that support a-FMT. For instance:

  1. Your microbiome is essential.

Your microbiome is as unique as a fingerprint, shaped by genetics and environmental influences, and fluctuates throughout your lifetime 1,19–28. A healthy microbiome is vital for many functions within the human body, including protecting against pathogens and modulation of the immune system 29–33. Unfortunately, our gut microbiome can be modified by things like antibiotics and other medications, lifestyle and what we eat 1,24–29,34, leading to something called “gut dysbiosis” 23,29,35,36. Gut dysbiosis has been associated with the development of diseases, infections and antibiotic resistance 29,36–42.

  1. Your microbiome is unique to you.

Your microbiome is unique to you, making you your best match. a-FMT allows you to harness what is unique about your individual microbiome, so it is ready for you to use in the future when you feel it is appropriate 4.

Your microbiome is unique, with high variability between individuals, and poor matching between donor and recipient may lead to gut disruption or FMT failure2,43–45. By banking your microbiome, you have the most physiologically relevant sample avoiding possible issues with donor matching 2,3,5,6,12–17.

  1. a-FMT can help restore your gut microbiome

a-FMT has been shown to be effective in restoring the gut microbiota diversity and recovering one’s original gut microbiota composition 2,4,6,33. By having a version of your own healthy microbiome ready, you have the capability to restore your gut to a healthy state4,6.

  1. Science is still researching the importance of the microbiome.

Research into the importance of the microbiome is growing, and the role that a-FMT can play in optimizing a healthy gut is a real focus of study3,46–49. Scientific and clinical research is looking to understand how our microbiome is not only crucial for maintaining our health but may also be uniquely effective in treating various conditions 17,29–33,40,50–53.

  1. Aging naturally leads to a deterioration in your microbiome

During aging, alterations in diet, medication and lifestyle have been shown to lead to changes in the gut microbiome 54-56. A growing body of evidence shows that the gut microbiome may be connected to many age-associated changes and play a role in longevity 57-59. Research indicates that as a natural part of aging, the composition of the gut microbiome significantly changes 60-62. Specifically, we lose the amount and diversity of bacteria in our gut microbiome during the aging process 55,58,63-65.

Based on current research, transplantation of a healthy and younger gut microbiome may have the potential to enhance the healthspan and lifespan 66–69. a-FMT has been shown to restore the diversity of the microbiome and maintaining a beneficial gut microbiome may help to manipulate the aging process1,4-6,68,70,71.

What is the Process if I want to do this? 

At Novel Biome, we have created a simple, safe and secure process to create long-lasting banking of your microbiome.

When you are ready to store your microbiome:

  1. When you sign up, Novel biome will send you a stool collection kit that stores and preserves your healthy sample and bacteria in the absence of oxygen, keeping your sample safe. This kit will detail the process of collecting your fecal sample.
  2. Once your sample is ready, you send the sample to Novel Biome in the provided pre-addressed mailing package.
  3. Once we receive your sample, we will immediately process and prepare it for long-term storage. You will receive confirmation that your sample has been safely processed and stored in 7-10 days of receiving your sample.
  4. When you are ready to request your a-FMT capsules, you can follow our simple request process, and we will ship your capsules to you.
  5. Upon receipt of your aFMT product, based on clinical research, you have the capability to restore your gut to a healthy state, as a-FMT has been shown to be effective in restoring the gut microbiota diversity and recovering one’s original gut microbiota composition 2,4,6,33.

Where and How is my Biome stored?

Novel Biome has established a world-class lab following the highest standards of Good Laboratory Practice. Following our manufacturing process to purify and isolate your microbiome, which will then be stored in a -80 degree Celsius medical freezer to preserve your microbiome over an extended period of time. 

How can I receive my own Microbiome back? 

Novel Biome makes the a-FMT process easy. 

  1. Fill out the attached request Form.
  2. We will process your request within 7 days and ship you’re a-FMT capsules to you at the address you provide as part of the request process. 
  3. You should receive your a-FMT capsules within 7-14 days from when you request them. If you feel you need them more immediately, please indicate as such on the request form and we will do our best to expedite the process. We will also send you simple instructions for home use.

What are the costs for this Service? 

Stool Kit / Shipping Label / Initial Encapsulation Fee

$1,000 USD

Annual Storage Fee

$300 USD

Return Shipping/Handling On Request

$150 USD

Total: $1,450 USD

*after 1 year, you will be billed $300/yr for each sample we have in storage until you either opt out or have your product returned for use

FAQs 

aFMT FAQs

No. In this instance, you should consider our regular FMT service which relies on highly-screened donors with a long history of established safety and efficacy. You may after FMT treatment consider banking your stool for later use.
No. We are very protective of your health information and data and will not share your personal data with anyone else.
The consideration to bank your microbiome is based on the premise that at this point in time, your gut and microbiome are healthier than they would otherwise be should you undergo a medical procedure or require the need for antibiotics. It’s likely you could improve your microbiome further, however, there is an advantage to storing your biome today to prepare you for a potential disruption to your microbiome. Should you decide in time that your microbiome is even better than when you initially submitted your sample, it is possible for you to submit another sample to be processed into capsules, although another processing fee would be required.
Yes. You would simply place several orders (shipped to one address) and collect each sample separately. We provide a 15% discount on orders of 4 or more kits.
As mentioned earlier, the microbiome is constantly changing based on environmental factors and aging. However, we at Novel Biome feel that it is extremely advantageous to have your microbiome banked in the event of later microbiome damage irrespective of age.
We at Novel Biome are currently doing our own research and stability studies to better understand the longevity of samples, and to measure the viability of the stored microbiome.
Yes, several days before submitting your stool sample, you could eat a very clean diet (ie. no sugars, processed foods, or alcohol, etc) and focus on eating as broad a diet as possible to expand the diversity of the microbes in your sample. This is based on research that has shown that dietary intake can rapidly alter the microbiome in as little as 24 hours18.
No. This sample is ONLY meant to be returned to and used by you!
We may be able to provide you with additional discounts depending on the volume of samples. Please email support@novelbiome.com to inquire.
We believe in this service and would be happy to have partners with a shared vision of health that wanted to back our brand and product assuming we have shared values. Please email support@novelbiome.com to explore the possibility of collaboration.

References 

1. Rinott, E. et al. 2021, 2. Bulow, C. et al. 2018, 3. Basson, A. R. et al. 2020, 4. Suez, J. et al. 2018, 5. Pérez-Matute, P. et al. 2020, 6. Taur, Y. et al. 2018, 7. Basson, A. et al. 2016, 8. Smillie, C. S. et al. 2018, 9. Li, S. S. et al. 2016, 10. Moayyedi, P. et al. 2017, 11. Malard, F. et al. 2021, 12. Lee, C. H. et al. 2019, 13. Schulz, M. D. et al. 2014, 14. Collins, S. M.et al. 2013, 15. Turnbaugh, P. J. et al. 2009, 16. Fei, N. & Zhao, L. 2013, 17. Vrieze, A. et al. 2012, 18. David, L. A. et al. 2014, 19. Hall, A. B. et al. 2017, 20. Odamaki, T. et al. 2016, 21. Perez-Muñoz, M. E.et al. 2017,  22. The Human Microbiome Project Consortium. 2012, 23. Wilson, B. C.et al. 2019, 24. Yatsunenko, T. et al. 2012, 25. Ussar, S. et al. 2015, 26. Goodrich, J. K. et al. 2014, 27. Wu, G. D. et al. 2011, 28. Turnbaugh, P. J. et al. 2006, 29. Choi, H. H. & Cho, Y.-S. 2016, 30. Hooper, L. V. et al. 2012, 31. Sommer, F. & Bäckhed, F. 2013, 32. Maynard, C. L. et al. 2012, 33. Buffie, C. G. & Pamer, E. G. 2013, 34. Britton, R. A. & Young, V. B. 2014, 35. Petersen, C. & Round, J. L. 2014, 36. Xu, M.-Q. 2015, 37. Johnson, D.et al. 2020, 38. Lee, L.-H. et al. 2019, 39. Lee, M. & Chang, E. B. 2021, 40. Ser, H.-L.et al. 2021, 41. Ternes, D. et al. 2020, 42. Pamer, E. G. 2016, 43. Bakken, J. S. et al. 2011, 44. Meighani, A. et al. 2016, 45. Fischer, M. et al. 2016, 46. Kootte, R. S. et al. 2017, 47. Terveer, E. M. et al. 2017, 48. Marchesi, J. R. et al. 2016, 49. Lau, A. W. Y. et al. 2021, 50. Aron-Wisnewsky, J. et al. 2019, 51. de Groot, P. F. et al. 2017, 52. Nowak, A. et al. 2019, 53. Allegretti, J. R. et al. 2019. 54. Claesson, M. J. et al. 2011, 55. Claesson, M. J. et al. 2012, 56. Kong, F. et al. 2019, 57. Badal, V. D. et al. 2020, 58. Bana, B. & Cabreiro, F. 2019, 59. Clemente, J. C. et al. 2012, 60. Askarova, S. et al. 2020, 61. Nagpal, R. et al. 2018, 62. Salazar, N. et al. 2017, 63. Kumar, M. et al. 2016, 64. Lynch, S. V. & Pedersen, O. 2016, 65. Odamaki, T. et al. 2016, 66. Bárcena, C. et al. 2019, 67. Fransen, F. et al. 2017, 68. Li, H., Ni, J. & Qing, H. 2021, 69. Smith, P. et al. 2017, 70. Kumar, M. et al. 2016, 71. Nagpal, R. et al. 2018.

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